Bromocriptine in Amenorrhoea	

From experience of treating a large number of amenorrhoeic hyperprolactinaemia women, the results of treating the first fifty-eight appear to be representative of the success that can be achieved with bromocriptine therapy. (Fig. 4.15). Within one month of starting therapy, a regular menstrual cycle is restored in approximately twenty-five per cent of patients. Within two months, regular menstrual cycling can be restored in over sixty per cent, and within ten months, in some eighty per cent. Those patients who did not have restoration of regular menstrual cycles (with only one or two exceptions) had previously undergone surgery or radiotherapy for their pituitary tumour – this rendered them gonadotrophin deficient. Thus, if hyperprolactinaemia is the cause of amenorrhoea, the chances of restoring normal gonadal function by medical therapy alone are extremely good.